Read more about Pulmonary Physiology for Pre-Clinical Students

Pulmonary Physiology for Pre-Clinical Students

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Andrew Binks, Roanoke, VA

Copyright Year: 2022

Publisher: Virginia Tech Publishing

Language: English

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Table of Contents

1: Fundamentals

2: Mechanics of the Lungs

3: Lung Volumes and Compliance

4: Distribution of Ventilation

5: Airflow and Airway Resistance

6: Dynamic Airway Compression

7: Fundamentals of Gas Exchange

8: Perfusion and Diffusion Limitations in Gas Exchange

9: Pulmonary Blood Flow

10: Pulmonary Capillaries and Non-Ventilatory Function

11: Arterial CO₂ and Ph

12: Alkalosis and Acidosis

13: Ventilation and Perfusion

14: The Alveolar Gas Equation and Alveolar-Arterial PO₂ Difference

15: Pulmonary Shunts

16: Gas Transport

17: Control of Breathing

18: Dyspnea

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  • About the Book

    Pulmonary Physiology for Pre-Clinical Students is an undergraduate medical-level resource for foundational knowledge of pulmonary physiology. This text is designed for a course pre-clinical undergraduate medical curriculum and it is aligned to USMLE(r) (United States Medical Licensing Examination) content guidelines. The text is meant to provide the essential information from these content areas in a concise format that would allow learner preparation to engage in an active classroom. Clinical correlates and additional application of content is intended to be provided in the classroom experience. This resource should be assistive to the learner later in medical school and for exam preparation given the material is presented in a succinct manner, with a focus on high-yield concepts.

    The 101-page text was created specifically for use by pre-clinical students at Virginia Tech Carilion School of Medicine and was based on faculty experience and peer review to guide development and hone important topics.

    Instructors reviewing, adopting, or adapting parts or the whole of the text are requested to register their interest at:

    Instructors and subject matter experts interested in and sharing their original course materials relevant to pre-clinical education are requested to join the instructor portal at

    Binks, Andrew., (2022). Pulmonary Physiology for Pre-Clinical Students, Roanoke: Virginia Tech Carilion School of Medicine. Licensed with CC BY NC-SA 4.0.

    About the Contributors


    Dr. Andrew Binks is a cardiopulmonary physiologist who gained his BSc (Hons) in Physiological Sciences at the University of Newcastle upon Tyne, then a MSc in Human and Applied Physiology from King’s College, London. He returned to Newcastle to do his PhD and study the underlying physiological mechanisms of dyspnea, the cardinal symptom of cardiopulmonary disease. He continued investigating dyspnea at Harvard School of Public Health as a postdoctoral fellow and then as a research scientist. After seven years at Harvard, Andrew took his first faculty position at the University of New England where he taught cardiovascular and pulmonary physiology to health profession and medical students. He continued to teach medical students their heart and lung physiology after moving to the University of South Carolina’s Medical School in Greenville where he also directed the school’s heart and lung pathophysiology courses. Andrew currently teaches heart and lung physiology and pathophysiology at Virginia Tech Carilion School of Medicine, directs the heart and lung pathophysiology course and has also served as the departmental director of faculty development.

    In his two decades of teaching medical physiology, Andrew has regularly drawn upon his dyspnea research experience to generate an active, clinically focused approach to medical education. This book is part of that approach and supports students preparing for class with the basic information with the intention to apply and contextualize that information in a guided case-based classroom experience.

    Andrew has published numerous peer-reviewed research papers and book chapters about dyspnea and about contemporary medical education. He has also given keynote presentations, faculty workshops and international webinars to promote effective medical education for the modern adult learner. 

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